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Bernard MairThe heart, the powerful and unceasing engine of the circulatory system, can be a mystery. Advanced medical imaging has replaced the need for invasive surgery for an up-close view of the organ, but even the best technology leaves doctors and researchers with gaps in their knowledge. University of Florida Mathematics Professor Bernard Mair, in collaboration with David R. Gilland, an associate professor in the College of Engineering’s Department of Nuclear and Radiological Engineering, has received a three-year, $600,000 grant from the National Institutes of Health to develop algorithms to fill those gaps.

Their research team is developing algorithms that will help radiologists make better decisions about the health of the heart wall and will better detect the abnormalities in motion produced by an ailing heart. To obtain an image of the heart through gated emission tomography, a patient is injected with a safe radioactive isotope that has a half-life of about two hours. This isotope, called a tracer, emits minute positrons, or positively charged particles.

Mair first became interested in positron emission tomography in 1995, after arriving at UF in 1989. He had lunch with a colleague from the College of Engineering, and the pair talked about beginning emission tomography research. “At the time, I thought this would be a mathematical area of research with practical applications,” Mair says. “Tomography produces a three-dimensional image of the heart or other organs by recording the effects of those energy waves produced by the decaying radioisotope in the organ and using numerical algorithms to invert the data.”

Mair says the tomographic imaging produces a higher resolution image than ultrasound, but it requires more equipment. Magnetic resonance imaging or MRI, perhaps the most commonly used method of visualizing the heart, provides complementary information. Unlike an MRI—which only shows the organ’s structure—positron emission tomography allows medical professionals to observe the metabolic functions of the organ.

The major difficulty, Mair says, is reducing the blurring of the reconstructed images caused by the complex motion of the beating heart. “Preliminary results of research, which relies on biomechanical models of cardiac motion and fairly sophisticated numerical algorithms, have demonstrated that their techniques can significantly improve the current technology.”

—Warren Kagarise and Buffy Lockette

Grants through the Division of Sponsored Research
April–May 2005
Total: $8,031,448

April–May 2005Total: $8,031,448

 

April 2005 Total: $3,651,557
Investigator Department Agency Award Title
SULLIVAN N S ADMINISTRATION U F RESEARCH FOUNDATION $4,000 MISSCELLANEOUS WORKSHOPS, CONFERENCES/ UFRF
AKINYEMI A; VILLALON L A AFRICAN & ASIAN LANGUAGES U S DEPT OF EDUCATION $72,000 FULBRIGHT-HAYS GROUP PROJECTS ABROAD
MULLIGAN C J ANTHROPOLOGY MULTIPLE SPONSORS $3,818 MULTIPLE SPONSORS - DNA TESTING
SCHMIDT P R ANTHROPOLOGY WENNER-GREN FDTN ANTHRO RES $4,500 SOLANGAARACHCHI FELLOWSHIP -ANCIENT IRON SMELTING TECHNOLOGYIN THE KIRI OYA AND MIRISGONI OYA BASINS IN THE DRY ZONE
SHIH C ANTHROPOLOGY NATIONAL SCIENCE FOUNDATION $33,134 FAMILY SYSTEMS AND THEIR DEMOGRAPHIC IMPLICATIONS: AN ANTHROPOLOGICAL STUDY OF FOUR CHINES ETHNIC GROUPS
GUSTAFSON B A ASTRONOMY U S NAVY NAVAL RESEARCH LABORATORY $4,058 COSMIC DUST RESEARCH
SOLTIS D E; SOLTIS P S BOTANY NATIONAL SCIENCE FOUNDATION $134,839 COLLABORATIVE RESEARCH: PATTERNS & MECHANISMS OF GENE EXPRESSION IN RECENT ALLOTETRAPLOIDS OF RECURRENT ORIGIN
BARTLETT R J CHEMISTRY UNIV OF MISSOURI U S ARMY $80,269 DETERMINATION OF POTENTIAL ENERGY SURFACES FOR ENERGETIC MOLECULES
BENNER S A CHEMISTRY MASSACHUSETTS GENERAL HOSPITAL NATIONAL SCIENCE FOUNDATION $203,022 DARWINIAN CHEMICAL SYSTEMS
DURAN R S CHEMISTRY U S AIR FORCE $9,880 TRANSMEMBRANE BIOPOLYMERS AT ENGINEERED SURFACES
DURAN R S CHEMISTRY U S AIR FORCE AFOSR $235,079 AN OPTICAL TRAP WORKSTATION FOR THE INVESTIGATION OF VESICLE FUSION PROCESSES
DURAN R S; SCOTT M J CHEMISTRY NATIONAL SCIENCE FOUNDATION $100,250 THE US/FRANCE REU SITE IN CHEMISTRY
KATRITZKY A R CHEMISTRY EXXONMOBIL CORPORATION RESEARCH & ENGINEERING COMPANY $31,743 JOINT RESEARCH INTO CHEMICAL ASPECTS OF PETROLEUM
KATRITZKY A R CHEMISTRY EXXONMOBIL CORPORATION RESEARCH & ENGINEERING COMPANY $30,629 JOINT RESEARCH INTO CHEMICAL ASPECTS OF PETROLEUM (AMENDMENT NO. 1 TO AGREEMENT #57821)
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $250 SOFTWARE RESEARCH SUPPORT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $408 SOFTWARE RESEARCH SUPPORT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $272 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $1,509 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $3,432 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $2,558 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $471 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $272 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $1,309 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $414 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY RENOVIS $133,897 SYNTHESIS OFCOMPOUNDS & REAGENTS
STEWART J D CHEMISTRY MERCK & COMPANY INC $20,727 MATERIAL TRANSFER AGREEMENT WITH MERCK - BIOLOGICALS
YOST R A CHEMISTRY FINNIGAN CORP $36,000 FUNDAMENTAL & INSTRUMENTAL STUDIES OF GC/MS/MS ON THE GCQ
BAUM R J CTR FOR APPLIED PHILOSOPHY MULTIPLE SOURCES $22,000 BUSINESS & PROFESSIONAL ETHICS JOURNAL
MCCRAE C S ; MARSISKE M CTR FOR GERONTOLOGICAL STUD NATL INSTITUTES OF HEALTH NIA - NATL INSTITUTE ON AGING $216,934 INTRAINDIVIDUAL VARIABILITY IN SLEEP AND COGNITIVE PERFORMANCE IN OLDER ADULTS WITH INSOMNIA
MILLS T L; MCDADE B E DIV OF STUD & SPECIAL PROGRAMS U S DEPT OF EDUCATION $368,696 UPWARD BOUND UNIVERSITY OF FLORIDA
GOLDMAN A C GEOGRAPHY U S DEPT OF EDUCATION $3,000 FLORIDA NETWORK FOR GLOBAL STUDIES TITLE VI NATIONAL RESOURCCENTER: CURRICULUM AWARD
THRALL G I GEOGRAPHY DEPT OF EDUCATION $15,714 GEOGRAPHIC ACCESS ANALYSIS STATE OF FLORIDA HIGHER EDUCATION SYSTEM
CHANNELL J E GEOLOGY JOINT OCEANOGRAPHIC INSTITUTE NATIONAL SCIENCE FOUNDATION $104,323 PARTICIPATION IN INTREGRATED OCEAN DRILLING PROGRAM
HODELL D A GEOLOGY JOINT OCEANOGRAPHIC INSTITUTE NATIONAL SCIENCE FOUNDATION $15,671 INTEGRATED OCEAN DRILLING PROGRAM, NORTH ATLANTIC CLIMARE 2:EXPIDITION 306 SALARY SUPPORT
HODELL D A; CURTIS J H GEOLOGY NATIONAL SCIENCE FOUNDATION $392,376 LAKE PETEN-ITZA DRILLING PROJECT, GUATEMALA: A TERRESTRIAL ARCHIVE OF NORTHERN NEOTROPICAL CLIMATE AND ENVIRONMENTAL...
MARTIN E E GEOLOGY NATIONAL SCIENCE FOUNDATION $240,845 DEEP WATER CIRCULATION DURING THE MIDDLE TO LATE MIOCENE CARBONATE CRASH
SHRIVASTAV R INST ADV STDY OF COMMUN PROCES NATL INSTITUTES OF HEALTH NIDCD - DEAFNESS & COMM DISORD $238,750 MEASURING BREATHINESS WITH AN AUDITORY PROCESSING MODEL
SHRIVASTAV R INST ADV STDY OF COMMUN PROCES NATL INSTITUTES OF HEALTH NIDCD - DEAFNESS & COMM DISORD $38,675 MEASURING BREATHINESS WITH AN AUDITORY PROCESSING MODEL
HAGER W W MATHEMATICS NATIONAL SCIENCE FOUNDATION $96,161 SPARSE MATRIX ALGORITHMS AND THEIR APPLICATION TO DUAL ACTIVE SET TECHNIQUES IN OPTIMIZATION
ANDRAKA B PHYSICS U S DEPT OF ENERGY $118,143 INVESTIGATION OF NOVEL STRONGLY CORELATED ELECTRON STATES WITH THE EMPHASIS ON PR-BASED SYSTEMS
AVERY P R PHYSICS NATIONAL SCIENCE FOUNDATION MULTIPLE SUBCONTRACTS $229,275 ITR/AP: AN INTERNATIONAL VIRTUAL-DATA GRID LABORATORY FOR DATA INTENSIVE SCIENCE
IHAS G G PHYSICS NASA $26,254 HYDROGEN RESEARCH FOR SPACEPORT AND SPACE BASED APPLICATIONS
IHAS G G PHYSICS NATIONAL SCIENCE FOUNDATION $21,693 24TH INTERNATIONAL CONFERENCE ON LOW TEMPERATURE PHYSICS (LT24)
SULLIVAN N S PHYSICS FLORIDA STATE UNIVERSITY NAT HIGH MAGNETIC FIELD LAB NATIONAL SCIENCE FOUNDATION $271,221 THE NATIONAL HIGH MAGNETIC FIELD LABORATORY
BJORNDAL K A; BOLTEN A B ZOOLOGY U F FOUNDATION $2,608 SEA TURTLE CONSERVATION
EVANS D H ZOOLOGY NATIONAL SCIENCE FOUNDATION $7,200 PARACRINE CONTROL OF FISH GILL FUNCTION
LILLYWHITE H B ZOOLOGY U F FOUNDATION $6,223 SEAHORSE KEY CONSERVATION
WAYNE M L ZOOLOGY UNIV OF CALIFORNIA DAVIS NATL INSTITUTES OF HEALTH $67,055 QUANTITATIVE GENOMICS OF SEXUAL DIMORPHISM

 

April 2005 Total: $4,379,891

Investigator Department Agency Award Title
FALSETTI A B ANTHROPOLOGY MULTIPLE SOURCES $436 FEES FOR SERVICES INCLUDING FORENSIC WORKSHOPS & CASE ANALYSIS
SHIH C ANTHROPOLOGY NATIONAL SCIENCE FOUNDATION $74,327 FAMILY SYSTEMS AND THEIR DEMOGRAPHIC IMPLICATIONS: AN ANTHROPOLOGICAL STUDY OF FOUR CHINES ETHNIC GROUPS
WARREN M W ANTHROPOLOGY MULTIPLE SPONSORS $822 MISCELLANEOUS DONORS
DERMOTT S F ASTRONOMY NASA $115,518 DYNAMICS OF INTERPLANETARY DUST PARTICLES
HAMANN III F ASTRONOMY SPACE TELESCOPE SCIENCE INST NASA $38,323 AALS IN QUASARS: DIAGNOSTICS OF THE ENVIRONMENT
LADA E A; ELSTON R J ASTRONOMY NATIONAL SCIENCE FOUNDATION $219,864 TOWARD A COMPLETE NEAR-IR SPECTROSCOPIC SURVEY OF GIANT MOLECULAR CLOUDS
REYES F J ASTRONOMY UNIVERSITY OF CENTRAL FLORIDA FL SPACE GRANT CONSORTIUM NASA $5,800 SUPPORT FOR EDUCATIONA ND PUBLIC OUTREACH PROGRAMS OF THE UFRADIO OBSERVATORY ON-LINE
SARAJEDINI A ASTRONOMY SPACE TELESCOPE SCIENCE INST NASA $45,002 THE STAR FORMATION HISTORY AND METALLICITY EVOLUTION OF M33: A COMPREHENSIVE STUDY OF DISK EVOLUTION
SARAJEDINI A ASTRONOMY SPACE TELESCOPE SCIENCE INST NASA $47,075 MAIN SEQUENCE TURNOFF AGES FOR SECOND PARAMETER CLUSTERS IN M33
GITZENDANNER M A; SOLTIS P S BOTANY U S DEPT OF THE INTERIOR FISH & WILDLIFE SERVICE $43,752 GENETIC RESEARCH CRUCIAL TO THE RECOVERY OF ZIZIPHUS CELATA
KITAJIMA K BOTANY NATIONAL SCIENCE FOUNDATION $1,720 CAREER: FUNCTIONAL BASES FOR THE TRADE-OFF BETWEEN GROWTH AND SURVIVAL OF TREE SEEDLINGS
KITAJIMA K BOTANY NATIONAL SCIENCE FOUNDATION $26,086 CAREER: FUNCTIONAL BASES FOR THE TRADE-OFF BETWEEN GROWTH AND SURVIVAL OF TREE SEEDLINGS
MACK M C BOTANY UNIV OF CALIFORNIA U C IRVINE NATIONAL SCIENCE FOUNDATION $62,259 CONTROLS OVER FUNGAL COMMUNITEIS AND CONSEQUENCES FOR NUTRIENT CYCLING
SOLTIS D E; SOLTIS P S BOTANY NATIONAL SCIENCE FOUNDATION $61,422 A COMPREHENSIVE PHYLOGENETIC TREE OF LIVING AND FOSSIL ANGIOSPERMS
KATRITZKY A R CHEMISTRY ARKAT USA $50,000 FLORIDA HETEROCYCLIC CONFERENCE AND ARKIVOC ELECTRONIC JOURNAL
KATRITZKY A R CHEMISTRY L'OREAL $192,871 LOREAL RESEARCH AGREEMENT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $1,090 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $13,090 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $314 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY MULTIPLE COMPANIES $2,049 MILES COMPOUND CONTRACT
KATRITZKY A R CHEMISTRY U S ARMY $157,525 DEVELOPMENT OF NEW NITRO HETEROCYCLIC COMPOUNDS
KATRITZKY A R CHEMISTRY U S NAVY $39,381 SYNTHETIC METHODS AND SYNTHESIS OF AXIO AND ACETYLENE- TERMINATED OLIGOMERS
REYNOLDS J R CHEMISTRY SRI INTERNATIONAL U S DEPT OF DEFENSE $89,466 HIHG CONTRAST REFLECTIVE ELECTROCHROMIC DEVICES
REYNOLDS J R CHEMISTRY VANDERBILT UNIVERSITY U S ARMY $62,263 ADVANCED CARBON NANOTECHNOLOGY CONSORTIUM: DISPLAYS AND DETECTORS
REYNOLDS J R CHEMISTRY WAKE FOREST UNIVERSITY U S AIR FORCE $179,647 AGILE RESPONSE COATINGS
RICHARDS N G CHEMISTRY NATL INSTITUTES OF HEALTH $39,154 MEASURING ASPARAGINE SYNTHETASE EXPRESSION IN LEUKEMIA
SCHANZE K S CHEMISTRY VANDERBILT UNIVERSITY U S ARMY $69,852 ADVANCED CARBON NANOTECHNOLOGY CONSORTIUM: DISPLAYS AND DETECTORS
SCHANZE K S CHEMISTRY WAKE FOREST UNIVERSITY U S AIR FORCE $106,361 AGILE RESPONSE COATINGS
TAN W CHEMISTRY NATIONAL SCIENCE FOUNDATION $190,344 NANOSCALE ARRAYS FOR DIRECT RNA PROFILING IN SINGLE CELLS & THEIR COMPARTMENTS
VALA M T CHEMISTRY UNIVERSITY OF CENTRAL FLORIDA $3,000 PREBIOTIC MOLECULES IN INTERSTELLER SPACE
VILLALON L A CTR FOR AFRICAN STUDIES U S DEPT OF EDUCATION $208,000 ADMINISTRATIVE: NATIONAL RESOURCE CENTER & FOREIGN LANGUAGE & AREA STUDIES FELLOWSHIPS
BAUM R J CTR FOR APPLIED PHILOSOPHY MULTIPLE SOURCES $3,000 BUSINESS & PROFESSIONAL ETHICS JOURNAL
HENRETTA J C CTR FOR GERONTOLOGICAL STUD UNIV OF MICHIGAN NATL INSTITUTES OF HEALTH $35,780 HEALTH AND RETIREMENT STUDY
CHANNELL J E GEOLOGY JOINT OCEANOGRAPHIC INSTITUTE NATIONAL SCIENCE FOUNDATION $10,357 INTREGRATED OCEAN DRILLING PROGRAM EXPEDITION 306: SALARY SUPPORT
HODELL D A GEOLOGY JOINT OCEANOGRAPHIC INSTITUTE NATIONAL SCIENCE FOUNDATION $44,172 INTRGRATED OCEAN DRILLING PROGRAM NORTH ATLANTIC 1, EXPEDITION 303: SALARY SUPPORT
HODELL D A GEOLOGY JOINT OCEANOGRAPHIC INSTITUTE NATIONAL SCIENCE FOUNDATION $7,640 UNDERGRADUATE SUPPLEMENTAL AWARD
HODELL D A GEOLOGY JOINT OCEANOGRAPHIC INSTITUTE NATIONAL SCIENCE FOUNDATION $40,979 INTRGRATED OCEAN DRILLING PROGRAM NORTH ATLANTIC 1, EXPEDITION 303: SALARY SUPPORT
MARTIN E E GEOLOGY AM CHEMICAL SOCIETY $79,400 WARM SALINE DEEP WATER PRODUCTION IN THE MIDDLE EOCENE TO EARLY OLIGOCENE
FREIFELD A HISTORY U S DEPT OF EDUCATION $3,222 FLORIDA NETWORK FOR GLOBAL STUDIES TITLE VI NATIONAL RESOURCCENTER PROPOSAL
MCCULLOUGH S A MATHEMATICS NATIONAL SCIENCE FOUNDATION $67,689 TOPICS IN DILATION THEORY
SHABANOV S; KLAUDER J R MATHEMATICS SCIENCE APPLICATIONS INTL CORP U S AIR FORCE $57,702 PROPAGATION OF NARROW ELECTROMAGNETIC BEAMS IN DISPERSIVE MEDIA
AVERY P R PHYSICS CALIFORNIA INST OF TECHNOLOGY NATIONAL SCIENCE FOUNDATION $168,294 ITR: ASE; INT: DMC: ULTRALIGHT: AN ULTRASCALE INFORMATION SYSTEM FOR DATA INTENSIVE RESEARCH
MITSELMAKHER G; KORYTOV A PHYSICS FERMILAB U S DEPT OF ENERGY $20,938 US CMS ENDCAP MUON M & O SUBSYSTEM FY 2004
MITSELMAKHER G; KORYTOV A PHYSICS FERMILAB U S DEPT OF ENERGY $15,847 ENDCAP MUON SYSTEM DEVELOPMENT FOR THE CMS PROJECT FY 2004
MITSELMAKHER G; KORYTOV A PHYSICS FERMILAB U S DEPT OF ENERGY $60,000 ENDCAP MUON SYSTEM DEVELOPMENT FOR THE CMS PROJECT FY 2004
MITSELMAKHER G; KORYTOV A PHYSICS FERMILAB U S DEPT OF ENERGY $70,000 ENDCAP MUON SYSTEM DEVELOPMENT FOR THE CMS PROJECT FY 2004
MITSELMAKHER G; KORYTOV A PHYSICS FERMILAB U S DEPT OF ENERGY $117,240 US CMS ENDCAP MUON M & O SUBSYSTEM FY 2004
MITSELMAKHER G; TANNER D B PHYSICS NATIONAL SCIENCE FOUNDATION $398,105 DETECTION OF GRAVITATIONAL WAVES: INTERFEROMETRY, DEVICES, MATERIALS, AND ANALYSIS FOR LIGO
MITSELMAKHER G; TANNER D B PHYSICS NATIONAL SCIENCE FOUNDATION $211,600 DETECTION OF GRAVITATIONAL WAVES: INTERFEROMETRY, DEVICES, MATERIALS, AND ANALYSIS FOR LIGO
MULLER G PHYSICS NATIONAL SCIENCE FOUNDATION $32,818 ADVANCED LIGO: RESEARCH ON MODE MATCHING AND CONTROL SYSTEMS
MULLER G; TANNER D B PHYSICS NASA $306,232 BENCHTOP EXPERIMENT TO STUDY LISA INTERFEROMETRY AND TO SUPPORT THE DEVELOPMENT OF DATA ANALYSIS METHODS FOR LISA
TANNER D B PHYSICS WAKE FOREST UNIVERSITY U S AIR FORCE $26,258 AGILE RESPONSE COATINGS
BRANCH M N PSYCHOLOGY NATL INSTITUTES OF HEALTH NIDA - NATL INST ON DRUG ABUSE $186,138 BEHAVIORAL DETERMINANTS OF COCAINE TOLERANCE
ROWLAND N E PSYCHOLOGY NATL INSTITUTES OF HEALTH NIAAA - ALCOHOL ABUSE & ALC $46,301 TIME RESOLUTION OF ETHANOL-INDUCED NEUROTRANSMISSION
PHARIES D A ROMANCE LANGUAGES U S DEPT OF EDUCATION $6,173 ADMINISTRATION: NATIONAL RESOURCE CENTERS AND FOREIGN LANGUAGE AND AREA STUDIES FELLOWSHIPS
HOBERT J P STATISTICS NATIONAL SCIENCE FOUNDATION $117,893 EXACT AND APPROXIMATE MARKOV CHAIN SAMPLING ALGORITHMS
BJORNDAL K A; ROARK A M ZOOLOGY NATIONAL SCIENCE FOUNDATION $11,800 PHYSIOLOGICAL AND LIFE-HISTORY RESPONSES TO VARIATION IN FOOD AVAILABILITY IN A PARTHENOGENETIC INSECT
LEVEY D J; ANDINO J M ZOOLOGY NATIONAL SCIENCE FOUNDATION ALACHUA COUNTY $76,500 SCIENCE PARTNERS IN INQUIRY-BASED COLLABORATIVE EDUCATION (S.P.I.C.E.)
OSENBERG C W ZOOLOGY SPRINGER-VERLAG $11,000 OECOLOGIA EDITORIAL OFFICE

This listing of grants is obtained from the Division of Sponsored Research in the Office of Research and Graduate Programs. While every effort to ensure accuracy has been made, mistakes sometimes happen. If you feel there is an error, please contact Greg Miller-House at gregmh@rgp.ufl.edu.

 

Photo:
Jane Dominguez

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